According to statistics, there are currently 537 million people with diabetes in the world. For these patients who need regular monitoring of blood sugar levels, there are limited conditions for home blood sugar testing, which means that most people can only collect blood sugar data in the doctor’s office, or under the doctor’s advice. Use of medical equipment.

However, with the development of home health management, more and more patients as well as lifestyle-conscious or fitness-based consumers are taking advantage of off-the-shelf technology to monitor their blood glucose. These at-home kits either require a finger prick to draw blood, or use a single-use probe on a patch on the outer layer of the skin.

rfid equipment

In response to the needs of the market, Seattle technology company Know Labs has developed an alternative called the Bio RFID platform, which uses radio frequency technology to transmit signals directly into the individual’s body and measure the response, allowing it to be read without damaging the skin. Identify blood sugar levels. The company has completed a series of studies over the past three years to validate its sensor technology.

Currently, Know Labs’ RFID platform solution is still in the research and development stage, and the technology has been verified internally and externally through clinical research. Although not yet approved, the solution is currently heading toward potential U.S. Food and Drug Administration evaluation. Currently, the company is continuing its own product development and validation.

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Testing Wideband RF Transmissions

Ron Erickson founded Know Labs with an early vision to use sensing and measurement technologies to better understand human health. The company’s goal is to provide a non-invasive alternative to blood glucose monitoring systems that require a subcutaneous connection to fluid under the skin. It started with Chroma ID, an optical-based sensing technology, whose configured LEDs showed early potential for measuring blood sugar in humans, Kent said. However, the limitations of optics caused some misery.

blood sugar

For example, the power requirements are too high, and the system is not flexible enough to measure different analytes in the same configuration. Therefore, launching it as a commercial and scalable product is not feasible. So the tech team revisited electromagnetic energy, and for its first iteration in 2018, using components from Wi-Fi routers and off-the-shelf wireless systems, it settled on radio frequency. A rapid prototyping process followed, during which Know Labs developed and tested different types of antenna arrays.

Ultimately, the company created an RF system without an antenna, and instead using an array of decoupling electrodes, the array generates an energy field directly around the sensor and can transmit and receive RF energy over a wide bandwidth. The system was internally tested with five participants and 92 samples. Participants ingested 37.5 grams (1.3 ounces) of liquid D-glucose and placed their forearms over a bio-RFID sensor.

The system then monitored their blood glucose levels every three hours using Dexcom’s G6 solution (the leading blood glucose monitoring system) as a comparison reference. The company also observed a mean absolute relative difference (MARD) of 20.6%. It also conducted a proof-of-principle study with the Mayo Clinic that included measurements of the response when water was used with isopropyl alcohol, when salt was used in the water, and when commercial bleach was used in the water. The system detects concentrations of 2,000 parts per million (ppm), and the team claims it can detect concentrations as high as 10,000 ppm.

How the technology RFID Equipment works

The technology could be built into a pocket-sized sensor device that runs on battery power and has a screen in the middle on which an individual can view blood glucose measurements, as well as via an app on their phone. Those who want to take measurements, such as after a meal or exercise, can turn the device on and hold it against the skin, then transmit RF signals through the device, and those responses will be influenced by molecules in blood vessels near the skin’s surface.

bio-rfid signatures

The sensor’s decoupled electrode array continuously sends data scans in the range of 500 to 1500 MHz at 0.1 MHz intervals, thereby collecting values at 10001 frequencies per scan. The algorithms tested so far are based on neural network models for predicting blood glucose readings. The software displays the measurements, known as bio-RFID signatures.

The device can be installed in a pocket-sized meter that users can carry with them, or it can be installed in other consumer devices such as watches. “It’s a form factor agnostic system,” Kent explained. The company is focused on building an independent business to manufacture and sell the resulting products, and intends to work with strategic partners for product integration.

“Our focus is to make the best possible non-invasive sensor,” Kent said, adding, “I think this technology is an important step in the advancement of human measurement and health, and it can become a self-contained device.” Once released , this technology could bring benefits to consumers and patients.


An immediate benefit, the company reports, is that blood sugar can be measured non-invasively, while it also reduces waste. Once released, this technology could provide benefits to consumers and patients. Kent reports that proof-of-concept, technical feasibility, and proof-of-principle studies have been completed, and research in the Know lab continues.

The latter focuses on the improvement and development of data collection algorithms, as well as understanding all scenarios in which the product may be used. Exact pricing has yet to be determined, though he expects the lack of supplies to keep costs down. The company holds more than 150 patents based on this technology, including decoupling electrode arrays.

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